This web page was produced as an assignment for Genetics 677, an undergraduate course at UW-Madison
Protein Homology
The species used were chosen due to the fact that they are all model organisms (C elegans, Chimpanzee, Mouse, Zebrafish, and Drosophila melanogaster) and humans. Homologs were found by reciprocal blasting against genderblind.
Caenorgabditis Elegans (Roundworm) - Amino Acid Transporter Family Member (aat-1)
All of the genderblind homologs look very similar. They all have the same Amino Acid Permease 2 domain that both genderblind and SLC7A11 have. This leads me to believe that the function of these proteins are important as they are well conserved across species. The differences between the homologs are at the ends of the proteins outside of the protein domain. The lengths of the end pieces are variable which could cause slight unknown changes in the functions of the proteins.